A) Five or more following symptoms presented for at 2 weeks period and represent a change from previous functioning: at least depressed mood or loss of interest or pleasure
1 - depressed mood most of the day, almost every day
2 - diminished pleasure or interest markedly in all or almost activities,most of the day, almost every day
3 - significant weight loss without dieting or weight gain or decrease in appetite almost every day
4 - insomnia or hypersomnia almost every day
5 - psychomotor agitation or retardation
6 - fatigue or loss of energy almost every day
7 - feelings of worthlessness or excessive and inappropriate guilt
8 - diminished ability to think or concentrate, or indecisiveness, nearly every day
9 - Recurrent thoughts of death, recurrent suicidal ideation without plan, or a suicide attempt or a specific plan for commiting suicide
B) symptoms do not meet criteria for a mixed episode
C) symptoms causes clinically significant distress or impairment in social, occupational, or other important areas or functioning
D) symptoms are not due to direct physiologic effects of a substance or general medical condition
E) Symptoms are not better accounted for by bereavement, or symptoms persist longer than 2 months orone characterized by marked functional impairment, morbid preoccupation with worthlessness, suicidal ideation, psychotic symptoms, or psychomotor retardation
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